Publicaciones (19) Publicaciones de Marta Varela Eirín

2024

  1. Converting cell death into senescence by PARP1 inhibition improves recovery from acute oxidative injury

    Nature Aging

2023

  1. High dietary protein and fat contents exacerbate hepatic senescence and SASP in mice

    FEBS Journal, Vol. 290, Núm. 5, pp. 1340-1347

2022

  1. Cellular senescence

    Current Biology

  2. Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression

    Cell death & disease, Vol. 13, Núm. 8, pp. 681

  3. Osteoarthritis: Mechanistic Insights, Senescence, and Novel Therapeutic Opportunities

    Bioelectricity, Vol. 4, Núm. 1, pp. 39-47

  4. Pharmacological CDK4/6 inhibition reveals a p53-dependent senescent state with restricted toxicity

    EMBO Journal, Vol. 41, Núm. 6

2021

  1. Algorithmic assessment of cellular senescence in experimental and clinical specimens

    Nature Protocols, Vol. 16, Núm. 5, pp. 2471-2498

  2. Connexin 43 and cellular senescence: New therapeutic strategies for treating osteoarthritis

    Revista de Osteoporosis y Metabolismo Mineral, Vol. 12, Núm. 4, pp. 152-154

  3. Molecular mechanisms of cellular senescence

    Regenerative Nephrology (Elsevier), pp. 221-230

  4. Physiological hypoxia restrains the senescence-associated secretory phenotype via AMPK-mediated mTOR suppression

    Molecular Cell, Vol. 81, Núm. 9, pp. 2041-2052.e6

2020

  1. A Senescence-Centric View of Aging: Implications for Longevity and Disease

    Trends in Cell Biology, Vol. 30, Núm. 10, pp. 777-791

  2. New therapeutic strategies for osteoarthritis by targeting sialic acid receptors

    Biomolecules, Vol. 10, Núm. 4

  3. Senolytic activity of small molecular polyphenols from olive restores chondrocyte redifferentiation and promotes a pro-regenerative environment in osteoarthritis

    Aging, Vol. 12, Núm. 16, pp. 15882-15905

2019

  1. A novel therapeutic target for osteoarthritis: Control of cellular plasticity and senescence using Connexin43

    Revista de Osteoporosis y Metabolismo Mineral, Vol. 11, Núm. 2, pp. 46-54

2018

  1. Cartilage regeneration and ageing: Targeting cellular plasticity in osteoarthritis

    Ageing Research Reviews, Vol. 42, pp. 56-71

  2. Targeting of chondrocyte plasticity via connexin43 modulation attenuates cellular senescence and fosters a pro-regenerative environment in osteoarthritis

    Cell Death and Disease, Vol. 9, Núm. 12

  3. Uniones celulares comunicantes

    Investigación y ciencia, Núm. 498, pp. 42-43

2017

  1. Recruitment of RNA molecules by connexin RNA-binding motifs: Implication in RNA and DNA transport through microvesicles and exosomes

    Biochimica et Biophysica Acta - Molecular Cell Research, Vol. 1864, Núm. 4, pp. 728-736

2016

  1. The C-terminal domain of connexin43 modulates cartilage structure via chondrocyte phenotypic changes

    Oncotarget, Vol. 7, Núm. 45, pp. 73055-73067