Publicaciones (165) Publicaciones de Miguel Anxo Maestro Saavedra

2023

  1. Design and synthesis of vitamin D analogs

    Feldman and Pike's Vitamin D: Volume One: Biochemistry, Physiology and Diagnostics (Elsevier), pp. 1013-1026

  2. Further Studies on the Highly Active Des-C-Ring and Aromatic-D-Ring Analogues of 1α,25-Dihydroxyvitamin D3 (Calcitriol): Refinement of the Side Chain

    Journal of Medicinal Chemistry, Vol. 66, Núm. 22, pp. 15326-15339

2022

  1. Design, Synthesis, Biological Activity, and Structural Analysis of Novel Des-C-Ring and Aromatic-D-Ring Analogues of 1α,25-Dihydroxyvitamin D3

    Journal of Medicinal Chemistry, Vol. 65, Núm. 19, pp. 13112-13124

  2. The Centennial Collection of VDR Ligands: Metabolites, Analogs, Hybrids and Non-Secosteroidal Ligands

    Nutrients, Vol. 14, Núm. 22

2021

  1. Design, Synthesis, Evaluation and Structure of Allenic 1α,25-Dihydroxyvitamin D3 Analogs with Locked Mobility at C-17

    Chemistry - A European Journal, Vol. 27, Núm. 53, pp. 13384-13389

2020

  1. Innovative three-step microwave-promoted synthesis of N-propargyltetrahydroquinoline and 1,2,3-triazole derivatives as a potential factor Xa (FXA) inhibitors: Drug design, synthesis, and biological evaluation.

    Molecules, Vol. 25, Núm. 3

2019

  1. Synthesis of 28,28,28-trideutero-25-hydroxydihydrotachysterol 2

    Journal of Steroid Biochemistry and Molecular Biology, Vol. 185, pp. 248-250

  2. Mechanistic insights for the transprotection of tertiary amines with Boc2O: Via charged carbamates: Access to both enantiomers of 2-azanorbornane-3- exo -carboxylic acids

    Organic Chemistry Frontiers, Vol. 6, Núm. 20, pp. 3540-3554

  3. Vitamin D and its synthetic analogs

    Journal of Medicinal Chemistry, Vol. 62, Núm. 15, pp. 6854-6875

2018

  1. Total synthesis of 1α,25-dihydroxyvitamin D 3 analogs modified at the side chain and D-ring

    Organic and Biomolecular Chemistry, Vol. 16, Núm. 24, pp. 4563-4569

  2. Stereoselective synthesis of 25S,26-dihydroxyvitamin D 3

    Journal of Steroid Biochemistry and Molecular Biology, Vol. 177, pp. 247-249

  3. Aromatic-Based Design of Highly Active and Noncalcemic Vitamin D Receptor Agonists

    Journal of Medicinal Chemistry, Vol. 61, Núm. 11, pp. 4928-4937

  4. Stereoselective Palladium-Catalyzed Approach to Vitamin D3 Derivatives in Protic Medium

    Chemistry - A European Journal, Vol. 24, Núm. 13, pp. 3314-3320

  5. Synthesis of Side-Chain Locked Analogs of 1α,25-Dihydroxyvitamin D3 Bearing a C17 Methyl Group

    Organic Letters, Vol. 20, Núm. 9, pp. 2641-2644

2017

  1. 1β,25-Dihydroxyvitamin D3: A new vitamin D metabolite in human serum

    Journal of Steroid Biochemistry and Molecular Biology, Vol. 173, pp. 341-348

  2. A new approach to 19-nor-A-ring phosphine oxide for the convergent synthesis of 19-nor-calcitriol

    Journal of Steroid Biochemistry and Molecular Biology, Vol. 173, pp. 86-88

  3. Total synthesis of 1α,25-dihydroxyvitamin D3 (calcitriol) through a Si-assisted allylic substitution

    Chemical Communications, Vol. 53, Núm. 58, pp. 8144-8147

2016

  1. Carborane-based design of a potent Vitamin D receptor agonist

    Chemical Science, Vol. 7, Núm. 2, pp. 1033-1037

  2. Stereoselective synthesis of 1β,25-Dihydroxyvitamin D3 and its 26,27-hexadeuterated derivative

    Journal of Steroid Biochemistry and Molecular Biology, Vol. 164, pp. 56-58

  3. Vitamin D receptor 2016: novel ligands and structural insights

    Expert Opinion on Therapeutic Patents, Vol. 26, Núm. 11, pp. 1291-1306