Gene Signatures Research Involved in Cancer Using Machine Learning

  1. Jose Liñares-Blanco 1
  2. Carlos Fernandez-Lozano 1
  1. 1 Universidade da Coruña
    info

    Universidade da Coruña

    La Coruña, España

    ROR https://ror.org/01qckj285

Libro:
XoveTIC 2019: The 2nd XoveTIC Conference (XoveTIC 2019), A Coruña, Spain, 5–6 September
  1. Alberto Alvarellos González (ed. lit.)
  2. José Joaquim de Moura Ramos (ed. lit.)
  3. Beatriz Botana Barreiro (ed. lit.)
  4. Javier Pereira Loureiro (ed. lit.)
  5. Manuel F. González Penedo (ed. lit.)

Editorial: MDPI

ISBN: 978-3-03921-444-0 978-3-03921-443-3

Año de publicación: 2019

Congreso: XoveTIC (2. 2019. A Coruña)

Tipo: Aportación congreso

Resumen

With the cheapening of mass sequencing techniques and the rise of computer technologies, capable of analyzing a huge amount of data, it is necessary nowadays that both branches mutually benefit. Transcriptomics, in this case, is a branch of biology focused on the study of mRNA molecules, among others. The quantification of these molecules gives us information about the expression that a gene is having at a given moment. Having information on the expression of the approximately 20,000 genes harbored by human beings is a really useful source of information for the study of certain conditions and/or pathologies. In this work, patient expression -omic data data have been used to offer a new analysis methodology through Machine Learning. The results of this methodology were compared with a conventional methodology to observe how they differed and how they resembled each other. These techniques, therefore, offer a new mechanism for the search of genetic signatures involved, in this case, with cancer.