Gene Signatures Research Involved in Cancer Using Machine Learning
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Universidade da Coruña
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- Alberto Alvarellos González (ed. lit.)
- José Joaquim de Moura Ramos (ed. lit.)
- Beatriz Botana Barreiro (ed. lit.)
- Javier Pereira Loureiro (ed. lit.)
- Manuel F. González Penedo (ed. lit.)
Editorial: MDPI
ISBN: 978-3-03921-444-0, 978-3-03921-443-3
Año de publicación: 2019
Congreso: XoveTIC (2. 2019. A Coruña)
Tipo: Aportación congreso
Resumen
With the cheapening of mass sequencing techniques and the rise of computer technologies, capable of analyzing a huge amount of data, it is necessary nowadays that both branches mutually benefit. Transcriptomics, in this case, is a branch of biology focused on the study of mRNA molecules, among others. The quantification of these molecules gives us information about the expression that a gene is having at a given moment. Having information on the expression of the approximately 20,000 genes harbored by human beings is a really useful source of information for the study of certain conditions and/or pathologies. In this work, patient expression -omic data data have been used to offer a new analysis methodology through Machine Learning. The results of this methodology were compared with a conventional methodology to observe how they differed and how they resembled each other. These techniques, therefore, offer a new mechanism for the search of genetic signatures involved, in this case, with cancer.